Intrauterine insemination

Intrauterine insemination is a fertility treatment that involves placing sperm inside a woman’s uterus to facilitate fertilization, it is a method that is close to natural insemination. The spermof a man, which has been prepared before the procedureis transfered into the uterus through a special catheter made of hypoallergenic, soft materials. Probably this is only one “unnatural” moment in the whole procedure. Then everything happens as usual – active sperms through the fallopian tubes get to the egg cell, meet with it and there is a fertilization process.

Contraindications for IUI for the woman:

♦ more than 40 years;
♦ somatic and mental diseases when pregnancy is contraindicated;
♦ uterine malformations or pathologies;
♦ tumours in the ovaries;
♦ malignant tumours of any localization;
♦ pathology of fallopian tubes;
♦ infection of genital tract;
♦ vaginal bleeding of unknown origin;
♦ operative procedures in the cavity of small pelvis in anamnesis;
♦ plural unsuccessful attempts of IUI (four and more);
♦ luteinization of non-ovulating follicle in two successive cycles;
♦ ovarian hyperstimulation syndrome (OHSS) in anamnesis;
♦ acute inflammatory diseases of any localization.

Intrauterine insemination can be provided by the sperm of the partner or donor. In the case of IUI involving donated sperm, only cryopreserved sperm may be used. The use of this sperm is only possible after receiving the repeated (in 6 monthsafterspermhandingover) negative results of the tests for HIV, syphilis and hepatitis.

Examination needed for the couple before IUI

For a woman it is obligatory:

♦ general and special gynecological examination;
♦ test for microflora from the cervical canal;
♦ cytological examination of cervicx;
♦ ultrasound examination of the pelvic organs;
♦ conclusion with a therapeutist;
♦ blood group test and Rh factor;
♦ clinical blood test, including coagulation time (valid for 1 month);
♦ blood test for syphilis, HIV infection, hepatitis B and C (valid for 3 months);
♦ blood tests on FSH, LH, AMH, estradiol, prolactin, testosterone, cortisol, progesterone, T3, T4, TSH;
♦ infectious disease tests (chlamydia, uro- and mycoplasmosis, herpes virus, cytomegaly, toxoplasmosis, rubella).

For a man it is obligatory:

♦ blood test for syphilis, HIV, hepatitis B and C (valid for 3 months);
♦ spermogram;
♦ blood group test and Rh factor;
♦ infectious analysis (chlamydia, uro-mycoplasmosis, herpes simplex virus, cytomegaly).

Also, for a married couple older than 35 years old, a genetic consultation is required.

The probability of pregnancy following intrauterine insemination (IUI) depends on many factors: the age of the woman, the duration of infertility, the quality of sperm, the results of the analysis, as well as the number of previous inseminations. The chances of getting pregnant are 10-15% for every attempt.

It is recommended to do no more than 3-4 attempts of insemination.Therefore, after ineffectiveness of 3-4 attempts of insemination we proceed the procedure in vіtro.

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